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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
28.48
Human Site:
S99
Identified Species:
41.78
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
S99
S
R
F
N
R
R
V
S
V
C
A
E
T
Y
N
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S173
N
R
F
T
R
R
A
S
V
C
A
E
A
Y
N
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
S157
N
R
F
T
R
R
A
S
V
C
A
E
A
Y
N
Dog
Lupus familis
XP_541890
401
45078
S96
S
R
F
D
R
R
V
S
V
C
A
E
T
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
S96
S
K
F
T
R
R
V
S
V
C
A
E
T
F
N
Rat
Rattus norvegicus
P12368
401
45522
S97
S
K
F
T
R
R
V
S
V
C
A
E
T
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
E66
L
F
K
N
L
D
P
E
Q
M
S
Q
V
L
D
Chicken
Gallus gallus
Q5ZM91
382
43332
R98
V
V
K
G
R
R
R
R
G
A
I
S
A
E
V
Frog
Xenopus laevis
NP_001084637
402
45172
S98
N
R
F
S
R
R
A
S
V
C
A
E
A
Y
N
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S96
S
R
F
N
R
R
V
S
V
C
A
E
A
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
A103
D
D
D
D
G
A
T
A
V
F
P
K
T
D
E
Honey Bee
Apis mellifera
XP_392905
383
43849
I104
E
E
D
D
G
L
K
I
V
H
P
K
T
D
A
Nematode Worm
Caenorhab. elegans
P30625
366
41449
I91
T
G
I
S
A
E
P
I
K
E
D
D
T
E
Y
Sea Urchin
Strong. purpuratus
Q26619
369
41770
L100
N
D
T
D
T
Q
K
L
V
Y
P
K
S
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
H137
S
T
P
P
L
P
M
H
F
N
A
Q
R
R
T
Red Bread Mold
Neurospora crassa
Q01386
385
42138
H110
D
N
W
S
P
P
V
H
P
K
T
A
E
Q
L
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
73.3
73.3
93.3
N.A.
80
80
N.A.
6.6
13.3
73.3
86.6
N.A.
13.3
13.3
6.6
6.6
P-Site Similarity:
100
80
80
100
N.A.
93.3
93.3
N.A.
26.6
13.3
86.6
93.3
N.A.
33.3
26.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
19
7
0
7
57
7
32
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% C
% Asp:
13
13
13
25
0
7
0
0
0
0
7
7
0
19
7
% D
% Glu:
7
7
0
0
0
7
0
7
0
7
0
50
7
13
13
% E
% Phe:
0
7
50
0
0
0
0
0
7
7
0
0
0
19
0
% F
% Gly:
0
7
0
7
13
0
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
13
0
0
7
0
0
0
0
% I
% Lys:
0
13
13
0
0
0
13
0
7
7
0
19
0
0
0
% K
% Leu:
7
0
0
0
13
7
0
7
0
0
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
25
7
0
19
0
0
0
0
0
7
0
0
0
0
50
% N
% Pro:
0
0
7
7
7
13
13
0
7
0
19
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
0
13
0
7
0
% Q
% Arg:
0
38
0
0
57
57
7
7
0
0
0
0
7
7
0
% R
% Ser:
38
0
0
19
0
0
0
50
0
0
7
7
7
0
0
% S
% Thr:
7
7
7
25
7
0
7
0
0
0
7
0
44
0
7
% T
% Val:
7
7
0
0
0
0
38
0
69
0
0
0
7
0
7
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
32
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _